RNA5SP305

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNA5SP305 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNA5SP305 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNA5SP305 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNA5SP305 expression acts as an unfavorable survival marker, although some lineages such as COAD and LGG show a favorable association.

UCEC, TGCT, and UCS are the cancer types where RNA5SP305 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSTertileII,III,IV0.1010.525<.001108view →
TGCTOSTertileIII,IV0.0031.000<.00172view →
UCSOSTertileII,III,IV0.0040.634<.00172view →
BLCADFSTertileAll0.3230.616.00636view →
COADDFSTertileII,III,IV0.9100.741.02230view →
READDFSTertileAll0.5060.828<.00127view →
CHOLOSTertileAll0.1540.793.00418view →
LGGOSTertileAll0.6340.408.00912view →
PRADOSTertileAll0.9760.996.00612view →
THYMOSTertileII,III,IV0.7040.982.0099view →
LIHCDFSTertileAll0.1770.450.0489view →
KICHOSTertileIII,IV0.1780.847<.0019view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration