Across TCGA pan-cancer cohorts, RNA5SP295 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNA5SP295’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNA5SP295 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP295 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
KIRC and COAD are the cancer types where RNA5SP295 tumor–normal differential expression is most reproducible.