RNA5SP290

Across TCGA pan-cancer cohorts, RNA5SP290 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNA5SP290’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNA5SP290 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP290 is over-expressed in tumor, although a few such as BRCA and KIRP show the opposite, repressed pattern.

THCA, BRCA, and KIRP are the cancer types where RNA5SP290 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP290 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	+0.259	.009	2	view →
BRCA	All	All	−0.214	.027	2	view →
KIRP	All	All	−0.291	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RNA5SP290–THCA

Open the THCA breakdown →