RNA5SP288

Across TCGA pan-cancer cohorts, RNA5SP288 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNA5SP288’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNA5SP288 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP288 is over-expressed in tumor, although a few such as LUSC and HNSC show the opposite, repressed pattern.

LUSC and HNSC are the cancer types where RNA5SP288 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP288 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	−0.304	.022	2	view →
HNSC	Female	IV	−0.488	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RNA5SP288–LUSC

Open the LUSC breakdown →