RNA5SP287

Across TCGA patient cohorts, RNA5SP287 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,804 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNA5SP287-associated GO terms across cancer lineages are Intrinsic apoptotic signaling pathway by p53 class mediator, Regulation of protein targeting, and Protein targeting to membrane. Each is linked with RNA5SP287 in more than 5 cancer types. Because this analysis shows association rather than direction, both RNA5SP287-to-partner and partner-to-RNA5SP287 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intrinsic apoptotic signaling pathway by p53 class mediator grouped by RNA5SP287-low versus RNA5SP287-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP287→partner) and Y-score (partner→RNA5SP287) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Intrinsic apoptotic signaling pathway by p53 class mediator →	+0.176	+0.111	<.001	.001	3	6
ESCA	Regulation of protein targeting →	+0.137	+0.101	<.001	.004	3	6
ESCA	Protein targeting to membrane →	+0.136	+0.179	<.001	<.001	3	6
ESCA	Cellular response to starvation →	+0.148	+0.135	<.001	.004	3	6
ESCA	Positive regulation of cell cycle process →	+0.158	+0.174	<.001	.003	3	5
ESCA	Regulation of keratinocyte proliferation →	+0.166	+0.194	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,804 associations by consensus.

Intrinsic apoptotic signaling pathway by p53 class mediator by RNA5SP287 expression — ESCA

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