Across TCGA pan-cancer cohorts, RNA5SP280 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNA5SP280 data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNA5SP280 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNA5SP280 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

TGCT, CHOL, and UCEC are the cancer types where RNA5SP280 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	All	0.672	0.991	<.001	72	view →
CHOL	DFS	Tertile	II,III,IV	0.016	0.406	<.001	72	view →
UCEC	DFS	Tertile	All	0.660	0.847	.002	60	view →
BRCA	OS	Tertile	II,III,IV	0.378	0.571	.001	57	view →
KICH	DFS	Tertile	II,III,IV	0.043	0.950	<.001	54	view →
HNSC	DFS	Tertile	II,III,IV	0.668	0.307	.018	54	view →
THCA	DFS	Tertile	IV	0.136	0.966	<.001	36	view →
SKCM	DFS	Tertile	II,III,IV	0.193	0.568	.010	33	view →
ESCA	OS	Quartile	IV	0.127	0.593	.008	33	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
SARC	OS	Tertile	All	0.311	0.771	.003	18	view →
UVM	OS	Tertile	All	0.345	0.706	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration

Same gene, other analysis: RNA5SP280 tumor-vs-normal RNA expression · all RNA5SP280 data types