Across TCGA pan-cancer cohorts, RNA5SP28 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RNA5SP28’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNA5SP28 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP28 is over-expressed in tumor.
KIRC, HNSC, and STAD are the cancer types where RNA5SP28 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP28 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.