RNA5SP278

Across TCGA patient cohorts, RNA5SP278 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,187 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNA5SP278-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, Regulation of RNA splicing, and RNA secondary structure unwinding. Each is linked with RNA5SP278 in more than 13 cancer types. Because this analysis shows association rather than direction, both RNA5SP278-to-partner and partner-to-RNA5SP278 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA splicing, via spliceosome grouped by RNA5SP278-low versus RNA5SP278-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP278→partner) and Y-score (partner→RNA5SP278) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of mRNA splicing, via spliceosome →	+0.049	+0.400	<.001	<.001	3	14
STAD	Regulation of RNA splicing →	+0.050	+0.417	<.001	<.001	3	13
ESCA	RNA secondary structure unwinding →	+0.048	+0.371	.003	.005	3	13
STAD	Peptidyl-lysine acetylation →	+0.044	+0.462	<.001	<.001	3	13
STAD	Regulation of DNA-templated transcription elongation →	+0.046	+0.477	<.001	<.001	3	13
STAD	Positive regulation of intracellular protein transport →	+0.044	+0.425	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,187 associations by consensus.

Regulation of mRNA splicing, via spliceosome by RNA5SP278 expression — ESCA

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