Across TCGA pan-cancer cohorts, RNA5SP277 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNA5SP277’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNA5SP277 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP277 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA and LUAD are the cancer types where RNA5SP277 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP277 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	All	−0.488	<.001	7	view →
LUAD	All	All	+0.190	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RNA5SP277 RNA expression & survival · all RNA5SP277 data types