RNA5SP268

Across TCGA patient cohorts, RNA5SP268 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,971 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible RNA5SP268-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Regulation of cilium assembly, and Negative regulation of organelle assembly. Each is linked with RNA5SP268 in more than 31 cancer types. Because this analysis shows association rather than direction, both RNA5SP268-to-partner and partner-to-RNA5SP268 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay grouped by RNA5SP268-low versus RNA5SP268-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP268→partner) and Y-score (partner→RNA5SP268) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.065	+0.521	<.001	<.001	2	32
DLBC	Regulation of cilium assembly →	+0.071	+0.361	<.001	<.001	3	29
DLBC	Negative regulation of organelle assembly →	+0.085	+0.343	<.001	<.001	3	29
DLBC	Regulation of telomere maintenance →	+0.068	+0.295	.001	.002	3	29
DLBC	RNA stabilization →	+0.053	+0.280	.001	.003	3	29
DLBC	Negative regulation of gene expression, epigenetic →	+0.083	+0.313	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,971 associations by consensus.

Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay by RNA5SP268 expression — DLBC

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