Across TCGA pan-cancer cohorts, RNA5SP259 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP259’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNA5SP259 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP259 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA, COAD, and UCEC are the cancer types where RNA5SP259 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP259 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.097	.012	3	view →
COAD	All	All	+0.179	.028	2	view →
UCEC	All	All	+0.118	.040	2	view →
STAD	All	IV	+0.803	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNA5SP259 RNA expression & survival · all RNA5SP259 data types