Across TCGA pan-cancer cohorts, RNA5SP25 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP25’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RNA5SP25 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP25 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

BLCA, KICH, and UCEC are the cancer types where RNA5SP25 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP25 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	All	+0.426	.015	6	view →
KICH	Male	All	−0.259	.012	3	view →
UCEC	All	IV	−1.160	.001	2	view →
KIRC	Male	All	+0.129	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNA5SP25 RNA expression & survival · all RNA5SP25 data types