RNA5SP233

Across TCGA patient cohorts, RNA5SP233 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,190 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNA5SP233-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Regulation of DNA repair, and Peptidyl-lysine modification. Each is linked with RNA5SP233 in more than 16 cancer types. Because this analysis shows association rather than direction, both RNA5SP233-to-partner and partner-to-RNA5SP233 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by RNA5SP233-low versus RNA5SP233-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP233→partner) and Y-score (partner→RNA5SP233) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of double-strand break repair →	+0.041	+0.492	<.001	<.001	3	17
STAD	Regulation of DNA repair →	+0.055	+0.585	<.001	<.001	3	17
UCEC	Peptidyl-lysine modification →	+0.039	+0.140	<.001	<.001	3	16
ESCA	Regulation of RNA splicing →	+0.057	+0.531	<.001	<.001	3	16
ESCA	Regulation of RNA export from nucleus →	+0.055	+0.540	<.001	<.001	3	16
ESCA	Regulation of mRNA splicing, via spliceosome →	+0.053	+0.453	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,190 associations by consensus.

Positive regulation of double-strand break repair by RNA5SP233 expression — ESCA

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