RNA5SP206

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA5SP206 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNA5SP206-associated genes across cancer lineages are INPP4B, PRDX1, and C-Raf. Each is linked with RNA5SP206 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNA5SP206-to-partner and partner-to-RNA5SP206 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by RNA5SP206-low versus RNA5SP206-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP206→partner) and Y-score (partner→RNA5SP206) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECINPP4B →-0.317-3.169.029.01832
UCECPRDX1 →+0.188+3.169.043.01932
SKCMC-Raf →+0.165+2.321.017.03532
COADTSC1 →-0.379-3.161.005.01931
COADBcl-xL →-0.243-3.144.038.01931
UCECJNK_pT183_Y185 →-0.182-3.321.016.01031
Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

INPP4B by RNA5SP206 expression — UCEC

Box plot of INPP4B in RNA5SP206-low vs RNA5SP206-high samples in UCEC.

Explore this box plot interactively →

Exploration