RNA5SP159

Across TCGA patient cohorts, RNA5SP159 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,508 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNA5SP159-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, DNA methylation-dependent heterochromatin formation, and Mitochondrial RNA metabolic process. Each is linked with RNA5SP159 in more than 12 cancer types. Because this analysis shows association rather than direction, both RNA5SP159-to-partner and partner-to-RNA5SP159 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by RNA5SP159-low versus RNA5SP159-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP159→partner) and Y-score (partner→RNA5SP159) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of gene expression, epigenetic →	+0.057	+0.514	<.001	<.001	3	13
ESCA	DNA methylation-dependent heterochromatin formation →	+0.061	+0.506	.001	<.001	3	13
ESCA	Mitochondrial RNA metabolic process →	+0.065	+0.647	.001	<.001	3	13
ESCA	Regulation of chromatin organization →	+0.063	+0.572	.003	<.001	2	13
ESCA	Negative regulation of stem cell differentiation →	+0.078	+0.560	<.001	<.001	3	12
ESCA	Steroid hormone mediated signaling pathway →	+0.053	+0.422	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,508 associations by consensus.

Negative regulation of gene expression, epigenetic by RNA5SP159 expression — ESCA

Explore this box plot interactively →