Across TCGA pan-cancer cohorts, RNA5SP131 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNA5SP131’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RNA5SP131 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP131 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD and LUSC are the cancer types where RNA5SP131 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP131 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	−0.583	<.001	7	view →
LUSC	Male	All	−0.450	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RNA5SP131 RNA expression & survival · all RNA5SP131 data types