RNA5SP116

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNA5SP116 RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNA5SP116 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNA5SP116 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNA5SP116 expression acts as an unfavorable survival marker.

BRCA, STAD, and LGG are the cancer types where RNA5SP116 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCADFSTertileII,III,IV0.4700.891<.00160view →
STADDFSTertileAll0.4600.671.00354view →
LGGOSTertileAll0.2040.799<.00118view →
PCPGDFSTertileAll0.0630.924<.00118view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RNA5SP116–BRCA (DFS)

Kaplan–Meier survival curve for RNA5SP116 RNA-high vs -low samples in BRCA.

Open the BRCA breakdown →

Exploration