RNA5-8SP6

Across TCGA pan-cancer cohorts, RNA5-8SP6 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNA5-8SP6 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RNA5-8SP6 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNA5-8SP6 expression acts as an unfavorable survival marker, although some lineages such as CESC and SKCM show a favorable association.

CESC, HNSC, and SKCM are the cancer types where RNA5-8SP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.871	0.706	.008	30	view →
HNSC	DFS	Tertile	IV	0.504	0.701	.004	21	view →
SKCM	OS	Tertile	II,III,IV	0.946	0.697	.014	12	view →
DLBC	OS	Tertile	II,III,IV	0.633	1.000	.001	9	view →
LIHC	OS	Tertile	II,III,IV	0.963	0.697	.016	9	view →
KICH	DFS	Tertile	All	0.600	0.907	.022	6	view →
COAD	DFS	Tertile	All	0.762	0.662	.035	6	view →
ESCA	OS	Median	II,III,IV	0.348	0.538	.034	4	view →
UCEC	OS	Quartile	All	0.897	0.936	.033	4	view →
BLCA	OS	Tertile	IV	0.676	0.432	.047	3	view →
LAML	DFS	Quartile	All	0.740	0.471	.045	2	view →
THYM	DFS	Quartile	All	1.000	0.618	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNA5-8SP6–CESC (DFS)

Open the CESC breakdown →