Across TCGA pan-cancer cohorts, RNA5-8SP2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5-8SP2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RNA5-8SP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5-8SP2 is over-expressed in tumor, although a few such as UCEC show the opposite, repressed pattern.

COAD, UCEC, and ESCA are the cancer types where RNA5-8SP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5-8SP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.466	.007	3	view →
UCEC	All	IV	−0.919	.001	2	view →
ESCA	All	II,III,IV	+0.339	.020	2	view →
BRCA	Female	All	+0.052	.047	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNA5-8SP2 RNA expression & survival · all RNA5-8SP2 data types