RNA5-8SN2

Across TCGA pan-cancer cohorts, RNA5-8SN2 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNA5-8SN2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNA5-8SN2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNA5-8SN2 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

KIRC, ESCA, and PAAD are the cancer types where RNA5-8SN2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.387	0.752	.003	84	view →
ESCA	OS	Tertile	II,III,IV	0.331	0.636	.002	80	view →
PAAD	DFS	Tertile	All	0.098	0.505	.002	45	view →
LUSC	OS	Tertile	II,III,IV	0.495	0.751	.004	33	view →
LGG	OS	Tertile	All	0.532	0.898	<.001	30	view →
GBM	OS	Tertile	All	0.298	0.437	.020	18	view →
OV	OS	Median	IV	0.886	0.623	.009	8	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNA5-8SN2–KIRC (DFS)

Open the KIRC breakdown →