Across TCGA pan-cancer cohorts, RN7SL646P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RN7SL646P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RN7SL646P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SL646P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
KIRC, BRCA, and THCA are the cancer types where RN7SL646P tumor–normal differential expression is most reproducible.