Across TCGA pan-cancer cohorts, RN7SL585P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RN7SL585P’s most consistent transcriptional readouts.
The strongest signal is observed in esophageal carcinoma (ESCA), where RN7SL585P RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SL585P is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.
ESCA, LUSC, and LUAD are the cancer types where RN7SL585P tumor–normal differential expression is most reproducible.