Across TCGA pan-cancer cohorts, RN7SL580P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RN7SL580P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where RN7SL580P RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SL580P is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.
KICH, KIRC, and KIRP are the cancer types where RN7SL580P tumor–normal differential expression is most reproducible.