RN7SL578P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RN7SL578P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RN7SL578P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RN7SL578P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SL578P is over-expressed in tumor, although a few such as KIRP and BRCA show the opposite, repressed pattern.

HNSC, KIRP, and BRCA are the cancer types where RN7SL578P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SL578P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCMaleIII,IV+0.080.0416view →
KIRPMaleIII,IV−0.127.0025view →
BRCAAllII,III,IV−0.024.0192view →
LIHCAllAll+0.040.0381view →
LUSCMaleAll−0.032.0211view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RN7SL578P–HNSC

Tumor-vs-normal expression box plot for RN7SL578P RNA in HNSC.

Open the HNSC breakdown →

Exploration