RN7SL546P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RN7SL546P RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RN7SL546P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RN7SL546P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SL546P is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

COAD, LUAD, and LUSC are the cancer types where RN7SL546P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SL546P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADAllII,III,IV+0.372.0016view →
LUADFemaleII,III,IV−0.510.0014view →
LUSCAllAll−0.185.0034view →
KICHAllAll−0.165.0034view →
THCAAllAll−0.111.0042view →
BRCAAllAll+0.088.0312view →
KIRCMaleAll−0.061.0262view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RN7SL546P–COAD

Tumor-vs-normal expression box plot for RN7SL546P RNA in COAD.

Open the COAD breakdown →

Exploration