RN7SL545P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RN7SL545P mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RN7SL545P-associated genes across cancer lineages are RNU5E-7P, RNU6-1318P, and RNU6-147P. Each is linked with RN7SL545P in more than 1 cancer types. Because this analysis shows association rather than direction, both RN7SL545P-to-partner and partner-to-RN7SL545P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5E-7P grouped by RN7SL545P-low versus RN7SL545P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RN7SL545P→partner) and Y-score (partner→RN7SL545P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU5E-7P →+0.850+6.453<.001.00131
UCECRNU6-1318P →+0.945+5.358<.001.00631
UCECRNU6-147P →+0.726+5.551<.001.00431
UCECRNU6-1324P →+1.318+4.982<.001.00931
UCECMIR516B1 →+0.845+5.081<.001.00831
UCECMIR548H3 →+1.108+5.299<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

RNU5E-7P by RN7SL545P expression — UCEC

Box plot of RNU5E-7P in RN7SL545P-low vs RN7SL545P-high samples in UCEC.

Explore this box plot interactively →

Exploration