Across TCGA pan-cancer cohorts, RN7SL503P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RN7SL503P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RN7SL503P RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SL503P is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
LUSC, UCEC, and HNSC are the cancer types where RN7SL503P tumor–normal differential expression is most reproducible.