Across TCGA pan-cancer cohorts, RN7SL498P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RN7SL498P’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RN7SL498P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SL498P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
BLCA and KICH are the cancer types where RN7SL498P tumor–normal differential expression is most reproducible.