Across TCGA pan-cancer cohorts, RN7SL478P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RN7SL478P’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where RN7SL478P RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SL478P is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
THCA, UCEC, and KICH are the cancer types where RN7SL478P tumor–normal differential expression is most reproducible.