Across TCGA pan-cancer cohorts, RN7SL477P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RN7SL477P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RN7SL477P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SL477P is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
KIRC, CHOL, and KIRP are the cancer types where RN7SL477P tumor–normal differential expression is most reproducible.