Across TCGA pan-cancer cohorts, RN7SL475P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RN7SL475P’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where RN7SL475P RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SL475P is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.
LUAD, LUSC, and UCEC are the cancer types where RN7SL475P tumor–normal differential expression is most reproducible.