Q-omics provides the consensus-scored RN7SL45P profile across patient tissues and cancer cell-line models. RN7SL45P expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, RN7SL45P is differentially expressed in 6, with the highest sampling consensus in KIRC. Additionally, RN7SL45P RNA expression shows 7,018 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight BRCA, KIRC, and ESCA as cancer lineages where RN7SL45P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RN7SL45P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RN7SL45P survival associations across molecular data types. RN7SL45P RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RN7SL45P RNA expression–survival associations across cancer types. High RN7SL45P expression shows unfavorable associations in MESO, LUSC, THCA, DLBC and UCS, but favorable associations in BRCA. The BRCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for RN7SL45P RNA expression.
This table summarizes RN7SL45P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for RN7SL45P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RN7SL45P shows lower tumor expression in KIRC, KIRP and THCA and higher tumor expression in BLCA, COAD and UCEC. The KIRC box plot shows higher RN7SL45P RNA expression in normal versus tumor tissue (log2 FC = −0.059, t-test p = .001).
This table shows molecular features associated with RN7SL45P in patient tissues and cancer cell lines. In patient samples, RN7SL45P shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
