RN7SL453P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RN7SL453P mutation is significantly associated with the RNA expression of many other genes, with 3,393 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RN7SL453P-associated genes across cancer lineages are RN7SKP60, LINC01201, and RNU7-176P. Each is linked with RN7SL453P in more than 2 cancer types. Because this analysis shows association rather than direction, both RN7SL453P-to-partner and partner-to-RN7SL453P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP60 grouped by RN7SL453P-low versus RN7SL453P-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RN7SL453P→partner) and Y-score (partner→RN7SL453P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRN7SKP60 →+0.233+5.368<.001.00533
SKCMLINC01201 →+0.471+4.634<.001.00332
HNSCRNU7-176P →+0.589+5.015.001.00932
HNSCRNU6-1183P →+1.050+5.124<.001.00832
UCECCRYBB2P1 →+0.495+2.960<.001<.00132
UCECJOSD1 →+0.506+2.938<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,393 associations by consensus.

RN7SKP60 by RN7SL453P expression — HNSC

Box plot of RN7SKP60 in RN7SL453P-low vs RN7SL453P-high samples in HNSC.

Explore this box plot interactively →

Exploration