RN7SL453P

Across TCGA patient cohorts, RN7SL453P mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RN7SL453P-associated genes across cancer lineages are ATM, 14-3-3_beta, and FoxM1. Each is linked with RN7SL453P in more than 1 cancer types. Because this analysis shows association rather than direction, both RN7SL453P-to-partner and partner-to-RN7SL453P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by RN7SL453P-low versus RN7SL453P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RN7SL453P→partner) and Y-score (partner→RN7SL453P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.548	-1.584	.002	.036	3	2
UCEC	14-3-3_beta →	-0.091	-2.295	.021	.033	3	1
UCEC	FoxM1 →	+0.255	+3.169	.011	.018	3	1
UCEC	G6PD →	-0.257	-3.308	.043	.009	3	1
UCEC	JNK2 →	+0.250	+1.584	.001	.036	3	1
UCEC	MSH2 →	-0.246	-2.295	.006	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

ATM by RN7SL453P expression — UCEC

Explore this box plot interactively →