Across TCGA pan-cancer cohorts, RN7SL445P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RN7SL445P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RN7SL445P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SL445P is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.
KIRC, KICH, and COAD are the cancer types where RN7SL445P tumor–normal differential expression is most reproducible.