RN7SL431P

Across TCGA pan-cancer cohorts, RN7SL431P RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RN7SL431P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RN7SL431P RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SL431P is over-expressed in tumor, although a few such as HNSC and LUSC show the opposite, repressed pattern.

HNSC, CHOL, and KIRC are the cancer types where RN7SL431P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SL431P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	−1.827	.001	8	view →
CHOL	All	II,III,IV	+1.745	<.001	5	view →
KIRC	All	All	+0.184	<.001	5	view →
LUSC	All	All	−0.347	.001	3	view →
KICH	Female	III,IV	−0.816	.002	1	view →
COAD	Female	IV	+0.755	.033	1	view →
LUAD	All	III,IV	−0.476	.015	1	view →
THCA	All	II,III,IV	−0.379	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RN7SL431P–HNSC

Open the HNSC breakdown →