Across TCGA pan-cancer cohorts, RN7SL375P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RN7SL375P’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RN7SL375P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SL375P is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.
BLCA and KIRP are the cancer types where RN7SL375P tumor–normal differential expression is most reproducible.