RN7SL319P

Across TCGA patient cohorts, RN7SL319P mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RN7SL319P-associated genes across cancer lineages are Notch1, STAT3_pY705, and ASNS. Each is linked with RN7SL319P in more than 1 cancer types. Because this analysis shows association rather than direction, both RN7SL319P-to-partner and partner-to-RN7SL319P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by RN7SL319P-low versus RN7SL319P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RN7SL319P→partner) and Y-score (partner→RN7SL319P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.191	+3.009	.004	.019	3	2
UCEC	STAT3_pY705 →	-0.468	-2.459	<.001	.020	3	2
UCEC	ASNS →	+0.462	+2.459	.008	.020	3	2
UCEC	PDCD4 →	-0.537	-2.459	.018	.020	2	2
UCEC	Annexin_VII →	-0.168	-2.459	.012	.020	3	1
UCEC	Tuberin_pT1462 →	+0.359	+3.331	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Notch1 by RN7SL319P expression — UCEC

Explore this box plot interactively →