Across TCGA pan-cancer cohorts, RN7SL16P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RN7SL16P’s most consistent transcriptional readouts.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where RN7SL16P RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SL16P is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.
PAAD are the cancer types where RN7SL16P tumor–normal differential expression is most reproducible.