Across TCGA pan-cancer cohorts, RN7SL141P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RN7SL141P’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where RN7SL141P RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SL141P is over-expressed in tumor, although a few such as BRCA and COAD show the opposite, repressed pattern.
BRCA and COAD are the cancer types where RN7SL141P tumor–normal differential expression is most reproducible.