Across TCGA pan-cancer cohorts, RN7SL131P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RN7SL131P’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where RN7SL131P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SL131P is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
LUAD and BRCA are the cancer types where RN7SL131P tumor–normal differential expression is most reproducible.