Across TCGA pan-cancer cohorts, RN7SL110P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RN7SL110P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RN7SL110P RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SL110P is over-expressed in tumor, although a few such as LUSC and BRCA show the opposite, repressed pattern.
LUSC and BRCA are the cancer types where RN7SL110P tumor–normal differential expression is most reproducible.