Across TCGA pan-cancer cohorts, RN7SKP94 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RN7SKP94’s most consistent transcriptional readouts.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where RN7SKP94 RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SKP94 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.
PAAD and BRCA are the cancer types where RN7SKP94 tumor–normal differential expression is most reproducible.