Across TCGA pan-cancer cohorts, RN7SKP69 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RN7SKP69’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RN7SKP69 RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SKP69 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

LUSC, THCA, and BRCA are the cancer types where RN7SKP69 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SKP69 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	−0.305	<.001	5	view →
THCA	All	All	−0.129	<.001	5	view →
BRCA	All	III,IV	−0.250	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RN7SKP69 RNA expression & survival · all RN7SKP69 data types