RN7SKP50

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RN7SKP50 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RN7SKP50 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RN7SKP50 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RN7SKP50 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, MESO, and ACC are the cancer types where RN7SKP50 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileIV0.9220.700.00296view →
MESOOSTertileII,III,IV0.3230.573.01354view →
ACCDFSTertileII,III,IV0.0730.640<.00136view →
LGGOSTertileAll0.6110.824<.00127view →
TGCTDFSTertileII,III,IV0.0880.917.01018view →
UCSOSTertileAll0.2010.583.03518view →
LUADOSTertileIII,IV0.4620.225.02316view →
SKCMDFSTertileIII,IV0.3850.653.02815view →
GBMOSTertileAll0.2370.435.0049view →
BRCAOSTertileAll0.9560.917.0406view →
ESCAOSQuartileIII,IV0.5490.300.0482view →
DLBCOSMedianII,III,IV1.0000.851.0391view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration