Across TCGA pan-cancer cohorts, RN7SKP44 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RN7SKP44’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RN7SKP44 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SKP44 is over-expressed in tumor, although a few such as BRCA and HNSC show the opposite, repressed pattern.
KIRC, BRCA, and THCA are the cancer types where RN7SKP44 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SKP44 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.