Across TCGA pan-cancer cohorts, RN7SKP38 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RN7SKP38’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RN7SKP38 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SKP38 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
KIRC, BLCA, and STAD are the cancer types where RN7SKP38 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SKP38 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.