Across TCGA pan-cancer cohorts, RN7SKP281 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RN7SKP281’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RN7SKP281 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SKP281 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

BRCA, COAD, and LIHC are the cancer types where RN7SKP281 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SKP281 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.106	.010	4	view →
COAD	Female	IV	−0.310	.004	2	view →
LIHC	All	All	+0.036	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RN7SKP281 RNA expression & survival · all RN7SKP281 data types