Across TCGA pan-cancer cohorts, RN7SKP208 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RN7SKP208’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where RN7SKP208 RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SKP208 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.
COAD, READ, and STAD are the cancer types where RN7SKP208 tumor–normal differential expression is most reproducible.