Across TCGA pan-cancer cohorts, RN7SKP140 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RN7SKP140’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RN7SKP140 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SKP140 is over-expressed in tumor.
KIRP and UCEC are the cancer types where RN7SKP140 tumor–normal differential expression is most reproducible.